BDBM414929 Preparation of 6-ethyl-3-(phenylamino)-2-(pyridin-4-yl)-1,5,6,7-tetrahydro-4H-indol-4-one::US10428044, Example 28

SMILES CCC1Cc2[nH]c(c(Nc3ccccc3)c2C(=O)C1)-c1ccncc1

InChI Key InChIKey=NNGVNKWVGLEQRT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 414929   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM414929(Preparation of 6-ethyl-3-(phenylamino)-2-(pyridin-...)
Affinity DataIC50: 5.93nMAssay Description:In a typical assay 11 different concentrations of each compound (0.1 nM, 0.33 nM, 1.1 nM, 3.8 nM, 13 nM, 44 nM, 0.15 μM, 0.51 μM, 1.7 μ...More data for this Ligand-Target Pair
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Date in BDB:
8/17/2020
Entry Details
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