BDBM414835 N,3-Dimethyl-N-(4-methylphenyl)-1-[(2R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoyl]piperidine-4-carboxamide; Mixture of Diastereomers::US10428024, Compound A6

SMILES CC1CN(CCC1C(=O)N(C)c1ccc(C)cc1)C(=O)[C@@](C)(O)C(F)(F)F

InChI Key InChIKey=SBLDEPIWKYKRKH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 414835   

Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Human)
Merck Patent

US Patent

LigandBDBM414835(N,3-Dimethyl-N-(4-methylphenyl)-1-[(2R)-3,3,3-trif...)Copy SMILESCopy InChI

Affinity DataIC50: 240nMAssay Description:The PDC inactivation assay is performed in Greiner 384-well microtiter plates and is used for high throughput screen. 4 μl of PDHK2 (human, rec,...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/17/2020
Entry Details
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