BDBM414439 US10435396, Example 18::rel-N-{6-Methoxy-2-[(1S,4S,5R)-2-methyl-2-azabicyclo[2.2.1]hept-5-yl]-2H-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide

SMILES COc1cc2nn(cc2cc1NC(=O)c1cccc(n1)C(F)(F)F)[C@@H]1C[C@@H]2C[C@H]1CN2C

InChI Key InChIKey=VALDNGKJYXDJQU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 414439   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandPNGBDBM414439(rel-N-{6-Methoxy-2-[(1S,4S,5R)-2-methyl-2-azabicyc...)
Affinity DataIC50: 2nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
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Date in BDB:
8/16/2020
Entry Details
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