BDBM414432 N-(2-{1-[2-(Dimethylamino)ethyl]piperidin-4-yl}-6-methoxy-2H-indazol-5-yl)-6-(trifluoromethyl)pyridine-2-carboxamide::US10435396, Example 9

SMILES COc1cc2nn(cc2cc1NC(=O)c1cccc(n1)C(F)(F)F)C1CCN(CCN(C)C)CC1

InChI Key InChIKey=NDABOOUWFLKWNO-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 414432   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent

LigandBDBM414432(N-(2-{1-[2-(Dimethylamino)ethyl]piperidin-4-yl}-6-...)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details
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