BDBM414421 N-[6-Methoxy-2-(piperidin-4-yl)-2H-indazol-5-yl]-6-(trifluoromethyl)pyridine-2-carboxamide::US10435396, Example 2

SMILES COc1cc2nn(cc2cc1NC(=O)c1cccc(n1)C(F)(F)F)C1CCNCC1

InChI Key InChIKey=VKFRWIYGVBBMTK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 414421   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandPNGBDBM414421(N-[6-Methoxy-2-(piperidin-4-yl)-2H-indazol-5-yl]-6...)
Affinity DataIC50: 1nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
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