BDBM414088 N-((1R,5S,8R)-3-((R)-7- methyl-6-(1H-pyrrolo- [2,3-b]pyridin-4-yl)- 5,6,7,8-tetrahydropyrido- [4,3-d]pyrimidin-4-yl)-3- azabicyclo[3.2.1]octan-8- yl)methanesulfonamide::US10421765, Example 74

SMILES C[C@@H]1Cc2ncnc(C3C[C@@H]4CC[C@H](C3)[C@@H]4NS(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12

InChI Key InChIKey=HDLHIYBZKVXCDE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 414088   

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM414088(US10421765, Example 74 | N-((1R,5S,8R)-3-((R)-7- m...)
Affinity DataIC50: 279nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
Go to US Patent