BDBM413868 4-(3-Oxa-8-azabicyclo[3.2.1]octane-8-carbonyl)-2-ethoxy-N ((R)-2-hydroxy-2-((S)-2-methyl-1,2,3,4-tetrahydroisoquinolin-3-yl)ethyl)benzamide 2,2,2-trifluoroacetate ::US10421743, Example 3

SMILES CCOc1cc(ccc1C(=O)NC[C@@H](C)[C@@H]1Cc2ccc(OC)cc2CN1C)C(=O)N1C2CCC1COC2

InChI Key InChIKey=XSRSMUJLODCILL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 413868   

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandPNGBDBM413868(US10421743, Example 3 | 4-(3-Oxa-8-azabicyclo[3.2....)
Affinity DataIC50: 1.01E+3nMAssay Description:The 6 μL reactions are run in Greiner brand black 384-well low volume assay plates. All reactions contained assay buffer (phosphate buffered sal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
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