BDBM413592 (2S) N-[(1S)-1-[[(1S)-2-(hydroxyamino)-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]-N-methyl-1-tetradecanoyl-pyrrolidine-2-carboxamide::US10414797, Comparative Example 22::US10414797, Example C22

SMILES CCCCCCCCCCCCCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NO

InChI Key InChIKey=TUERMRRNMUNKFA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 413592   

TargetMetalloproteinase inhibitor 2(Long-tailed dwarf hamster)
Iproteos

US Patent
LigandPNGBDBM413592(US10414797, Comparative Example 22 | (2S) N-[(1S)-...)
Affinity DataIC50: 4.80E+3nMAssay Description:MMP-2: Recombinant MMP-2 expressed in Chinese hamster ovary (CHO) cells was obtained from Merck-Millipore (catalog number PF023-5UG). DQ gelatin from...More data for this Ligand-Target Pair
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In Depth
Date in BDB:
8/2/2020
Entry Details
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TargetMatrix metalloproteinase-9(Human)
Iproteos

US Patent
LigandPNGBDBM413592(US10414797, Comparative Example 22 | (2S) N-[(1S)-...)
Affinity DataIC50: 1.20E+3nMAssay Description:MMP-9: Recombinant MMP-9 expressed was obtained from Merck-Millipore (catalog number PF140-5UG, used in examples 1 to 9 and comparative examples) and...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
8/2/2020
Entry Details
Go to US Patent