BDBM413221 (R)-4-(1-(5-(4-ethyl-3-methylpiperazine-1-carbonyl)pyridin-2-yl)-5-hydroxy-1H-pyrazol-4-yl)-2-fluoro-3-methylbenzonitrile::US10407409, Example 338

SMILES CCN1CCN(C[C@H]1C)C(=O)c1ccc(nc1)-n1ncc(c1O)-c1ccc(C#N)c(F)c1C

InChI Key InChIKey=SCUUFDLZFXDHAW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 413221   

TargetEgl nine homolog 1 [181-417](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413221((R)-4-(1-(5-(4-ethyl-3-methylpiperazine-1-carbonyl...)
Affinity DataIC50: 3.98nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand InfoSimilars
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Date in BDB:
7/27/2020
Entry Details
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