BDBM413133 4-(1-(5-(4-cyclopropyl-1,4-diazepane-1-carbonyl)pyridin-2-yl)-5-hydroxy-1H-pyrazol-4-yl)-2-fluoro-3-methylbenzonitrile::US10407409, Example 323

SMILES Cc1c(F)c(ccc1-c1cnn(c1O)-c1ccc(cn1)C(=O)N1CCCN(CC1)C1CC1)C#N

InChI Key InChIKey=SGEXNVZZGGTYMM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 413133   

TargetEgl nine homolog 1 [181-417](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413133(4-(1-(5-(4-cyclopropyl-1,4-diazepane-1-carbonyl)py...)
Affinity DataIC50: 4.68nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand InfoSimilars
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Date in BDB:
7/27/2020
Entry Details
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