BDBM412731 2-[(1-Methyl-4-phenyl- imidazol-2- yl)methoxy]-7,8- dihydro-6H- cyclopen- ta[1,2]imidazo[3,4- c]pyridazine::Roche-Dataset for PDE10A, Compound 282::US10399985, Example 44

SMILES Cn1cc(nc1COc1ccc2nc3CCCc3n2n1)-c1ccccc1

InChI Key InChIKey=UMFVDPMHCFJPCE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 412731   

LigandPNGBDBM412731(US10399985, Example 44 | 2-[(1-Methyl-4-phenyl- im...)
Affinity DataIC50: 47nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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In Depth
Date in BDB:
7/27/2020
Entry Details
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LigandPNGBDBM412731(US10399985, Example 44 | 2-[(1-Methyl-4-phenyl- im...)
Affinity DataIC50: 47nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/28/2022
Entry Details Article
PubMed