BDBM412695 2- (Difluoromethyl)- 3-methyl-6-((1- methyl-4-phenyl- 1H-imidazol-2- yl)ethynyl)imidazo [1,2-b]pyridazine::US10399985, Example 7

SMILES Cc1c(nc2ccc(nn12)C#Cc1nc(cn1C)-c1ccccc1)C(F)F

InChI Key InChIKey=QFLLCXKNGXVARH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 412695   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Hoffmann-La Roche

US Patent

LigandBDBM412695(US10399985, Example 7 | 2- (Difluoromethyl)- 3-met...)Copy SMILESCopy InChI

Affinity DataIC50: 46.6nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoSimilars

In Depth
Date in BDB:
7/27/2020
Entry Details
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