BDBM412663 US10399974, Example 61

SMILES CCOc1cc(ccc1Nc1ncc2cc(C)nc(N3CC(C)(C3)OCC)c2n1)-c1nncn1C

InChI Key InChIKey=AYRXEHVCHSSPHZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 412663   

TargetDual specificity protein kinase TTK(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM412663(US10399974, Example 61)
Affinity DataIC50: 4nMAssay Description:The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent