BDBM412423 N-(5-(2-chloro-5-(1-methyl-1H- pyrazol-4-yl)phenyl)pyrazin-2-yl)-4- methylnicotinamide::US10399967, Compound 142::US10399967, Compound 53

SMILES Cc1ccncc1C(=O)Nc1cnc(cn1)-c1cc(ccc1Cl)-c1cnn(C)c1

InChI Key InChIKey=SRHINFVKXQDHJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 412423   

TargetInterleukin-2(Human)
Prcl Research

US Patent
LigandPNGBDBM412423(US10399967, Compound 142 | N-(5-(2-chloro-5-(1-met...)
Affinity DataIC50: 38nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
Prcl Research

US Patent
LigandPNGBDBM412423(US10399967, Compound 142 | N-(5-(2-chloro-5-(1-met...)
Affinity DataIC50: 23nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent