BDBM412369 US10399961, Example 14

SMILES C[C@H]1CCN(C1)c1ccc(Cn2cc(C(=O)N[C@@H]3CCc4nc(N)ccc34)c(n2)C(F)(F)F)cn1

InChI Key InChIKey=IYWOLFDPAKKHGW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 412369   

TargetPlasma kallikrein(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM412369(US10399961, Example 14)
Affinity DataIC50: 40nMAssay Description:Human KLKB1 (0.01 U/mL; Enzyme Research Laboratories) or rat KLKB1 (0.625 nM; produced in-house) was incubated for 1 hr at Room Temperature with 0.10...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent