BDBM412357 1-(2-Methyl-quinolin-6-ylmethyl)-1H-[1,2,3]triazole-4-carboxylic acid (2-amino-5,6,7,8-tetrahydro-quinolin-5-yl)-amide::US10399961, Example 1

SMILES Cc1ccc2cc(Cn3cc(nn3)C(=O)NC3CCCc4nc(Cl)ccc34)ccc2n1

InChI Key InChIKey=IRDYSCISPDGSNH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 412357   

TargetPlasma kallikrein(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM412357(US10399961, Example 1 | 1-(2-Methyl-quinolin-6-ylm...)
Affinity DataIC50: 900nMAssay Description:Human KLKB1 (0.01 U/mL; Enzyme Research Laboratories) or rat KLKB1 (0.625 nM; produced in-house) was incubated for 1 hr at Room Temperature with 0.10...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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