BDBM412161 US10392405, Compound Id 1.025::US11059834, Compound 1.025

SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCCC[C@@H](CO)NCc3cc2Cl)cccc1-c1cccc(OCCCN2CCC(F)CC2)c1C

InChI Key InChIKey=ZTDWYBLKBRVVKA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 412161   

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM412161(US10392405, Compound Id 1.025 | US11059834, Compou...)
Affinity DataIC50: 100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/20/2020
Entry Details
Go to US Patent

LigandPNGBDBM412161(US10392405, Compound Id 1.025 | US11059834, Compou...)
Affinity DataIC50: 100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/2/2022
Entry Details
Go to US Patent