BDBM412143 US10392405, Compound Id 1.007::US11059834, Compound 1.007::US11691985, Compound 1.007

SMILES OC(=O)[C@@H]1CCCCNC(=O)c2cncc(COc3cc(O[C@H]4CCc5c4cccc5-c4ccccc4F)c(Cl)cc3CN1)c2

InChI Key InChIKey=DAYMDSLCYJUDNX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 412143   

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM412143(US10392405, Compound Id 1.007 | US11059834, Compou...)
Affinity DataIC50: 110nMAssay Description:Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
8/6/2023
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM412143(US10392405, Compound Id 1.007 | US11059834, Compou...)
Affinity DataIC50: 300nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/20/2020
Entry Details
Go to US Patent

LigandPNGBDBM412143(US10392405, Compound Id 1.007 | US11059834, Compou...)
Affinity DataIC50: 300nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/2/2022
Entry Details
Go to US Patent