BDBM412141 US10392405, Compound Id 1.005::US11059834, Compound 1.005::US11691985, Compound 1.005

SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCCC[C@H](NCc3cc2Cl)C(O)=O)cccc1-c1cccc(OCCCCl)c1C

InChI Key InChIKey=FXYPYMOGYBNLAF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 412141   

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM412141(US10392405, Compound Id 1.005 | US11059834, Compou...)
Affinity DataIC50: 200nMAssay Description:Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
8/6/2023
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM412141(US10392405, Compound Id 1.005 | US11059834, Compou...)
Affinity DataIC50: 1.03E+4nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/20/2020
Entry Details
Go to US Patent

LigandPNGBDBM412141(US10392405, Compound Id 1.005 | US11059834, Compou...)
Affinity DataIC50: 1.03E+4nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/2/2022
Entry Details
Go to US Patent