BDBM411417 N-(3-((3R,4R)-1-((R)-2-cyclopentylpropanoyl)- 3-methylpiperidin-4-yl)-1-methyl-1H-indol-5- yl)-2-ethoxybenzenesulfonamide::US10385036, Example 33

SMILES CCOc1ccccc1S(=O)(=O)Nc1ccc2n(C)cc([C@@H]3CCN(C[C@@H]3C)C(=O)[C@H](C)C3CCCC3)c2c1

InChI Key InChIKey=UREXSBIPNNKYDO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411417   

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandPNGBDBM411417(US10385036, Example 33 | N-(3-((3R,4R)-1-((R)-2-cy...)
Affinity DataIC50: 1.10nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
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