BDBM411411 (R)-2-ethoxy-N-(1-methyl-3-(1-(2,3,3- trimethylbutanoyl)piperidin-4-yl)-1H-indol-5- yl)benzenesulfonamide::US10385036, Example 27

SMILES CCOc1ccccc1S(=O)(=O)Nc1ccc2n(C)cc(C3CCN(CC3)C(=O)[C@H](C)C(C)(C)C)c2c1

InChI Key InChIKey=IJGFEKYRPKEHBF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411411   

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandPNGBDBM411411(US10385036, Example 27 | (R)-2-ethoxy-N-(1-methyl-...)
Affinity DataIC50: 1.70nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
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