BDBM411403 (R)-N-(3-(1-(cyclopentanecarbonyl)-2,2-dimethylpiperdin-4-yl)-1-methyl-1H-indol-5H-yl)-4-fluorobenzenesulfonamide::US10385036, Example 19

SMILES Cn1cc([C@@H]2CCN(C(=O)C3CCCC3)C(C)(C)C2)c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12

InChI Key InChIKey=PPOCSYDWYNGNDJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411403   

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandPNGBDBM411403(US10385036, Example 19 | (R)-N-(3-(1-(cyclopentane...)
Affinity DataIC50: 3.70nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
Go to US Patent