BDBM411400 (S)-N-(3-(1-(2,3-dimethylbutanoyl)pipendin-4-yl)-1- methyl-1H-indol-5-yl)-4-fluorobenzenesulfonamide::US10385036, Example 16

SMILES CC(C)[C@H](C)C(=O)N1CCC(CC1)c1cn(C)c2ccc(NS(=O)(=O)c3ccc(F)cc3)cc12

InChI Key InChIKey=OONBVMHCJRJLDR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411400   

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandPNGBDBM411400(US10385036, Example 16 | (S)-N-(3-(1-(2,3-dimethyl...)
Affinity DataIC50: 3.10nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
Go to US Patent