BDBM411385 Preparation of 4-fluoro-N-(1-methyl-3-((3R,4R)-3-methyl-1-((R)-2,3,3-trimethylbutanoyl)piperidin-4-yl)-1H-indol-5-yl)benzenesulfonamide::US10385036, Example 1

SMILES C[C@@H](C(=O)N1CC[C@H]([C@@H](C)C1)c1cn(C)c2ccc(NS(=O)(=O)c3ccc(F)cc3)cc12)C(C)(C)C

InChI Key InChIKey=PATOGJWQBSINFF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411385   

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandPNGBDBM411385(US10385036, Example 1 | Preparation of 4-fluoro-N-...)
Affinity DataIC50: 8.20nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
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