BDBM410778 6-[3-(2,6-dichlorobenzoyl)indazol-1-yl]pyridine-3-carboxylic acid ::US10383850, Compound 16

SMILES OC(=O)c1ccc(nc1)-n1nc(C(=O)c2c(Cl)cccc2Cl)c2ccccc12

InChI Key InChIKey=IXXBSLLJCKQTSB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 410778   

TargetNuclear receptor ROR-gamma(Human)
Orca Pharmaceuticals

US Patent
LigandPNGBDBM410778(6-[3-(2,6-dichlorobenzoyl)indazol-1-yl]pyridine-3-...)
Affinity DataIC50: 250nMAssay Description:The assay was run in black 384 well plates (Greiner cat no: 784900). Various concentrations of test ligands in 0.1 microliters DMSO were dispensed to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
Go to US Patent