BDBM410198 US10370379, Compound 15

SMILES NC(=O)c1cc(F)cc(c1)[C@H]1C[C@H](F)CN1c1nc2c(cnn2cc1F)C#N

InChI Key InChIKey=ZILGMLTVSJMUDM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 410198   

TargetHigh affinity nerve growth factor receptor(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM410198(US10370379, Compound 15)
Affinity DataIC50: 10nMAssay Description:In each well of a 384-well plate, 1 nM-1.5 nM of wild type NTRK1 enzyme (BPS Bioscience; 40280) was incubated in a total of 12.5 μL of buffer (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent