BDBM409855 US10370333, Example IV-26

SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1cncc(c1)C(N)=O

InChI Key InChIKey=SBAITEDLNTYIOE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 409855   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Sanford-Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM409855(US10370333, Example IV-26)
Affinity DataIC50: 100nMAssay Description:To determine the inhibition selectivity for inhibitor candidates, human TNAP, PLAP or IAP were added to microtiter plates followed by addition of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent

TargetIntestinal-type alkaline phosphatase(Human)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandPNGBDBM409855(US10370333, Example IV-26)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of IAP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAlkaline phosphatase, placental type(Human)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandPNGBDBM409855(US10370333, Example IV-26)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of PLAP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Sanford-Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM409855(US10370333, Example IV-26)
Affinity DataIC50: 105nMAssay Description:Inhibition of TNAP (unknown origin) in whole blood using pNPP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Sanford-Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM409855(US10370333, Example IV-26)
Affinity DataIC50: 16nMAssay Description:Inhibition of TNAP (unknown origin) using PPi as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed