BDBM409818 US10370333, Example III-39

SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1cncc(c1)-c1ccccc1C

InChI Key InChIKey=SIYAXDGSAHOGFK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 409818   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Sanford-Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM409818(US10370333, Example III-39)
Affinity DataIC50: 1.00E+3nMAssay Description:To determine the inhibition selectivity for inhibitor candidates, human TNAP, PLAP or IAP were added to microtiter plates followed by addition of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Sanford-Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM409818(US10370333, Example III-39)
Affinity DataIC50: 178nMAssay Description:Inhibition of TNAP (unknown origin) using PPi as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed