BDBM409622 2-[6-(2,4-Difluoro-3-methyl-phenyl)-3-fluoro-pyrrolo[3,2-::US10377753, Example 488

SMILES Cc1c(F)ccc(-c2cnc3c(F)cn(CC(=O)N4CC(F)C4)c3c2)c1F

InChI Key InChIKey=WYKKLPBVBXTCAA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 409622   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409622(2-[6-(2,4-Difluoro-3-methyl-phenyl)-3-fluoro-pyrro...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent