BDBM40958 (6E)-6-[2-amino-5-(4-methoxyphenyl)-1H-pyrimidin-6-ylidene]-3-methoxy-1-cyclohexa-2,4-dienone::(6E)-6-[2-amino-5-(4-methoxyphenyl)-1H-pyrimidin-6-ylidene]-3-methoxy-cyclohexa-2,4-dien-1-one::(6E)-6-[2-amino-5-(4-methoxyphenyl)-1H-pyrimidin-6-ylidene]-3-methoxycyclohexa-2,4-dien-1-one::(6E)-6-[2-azanyl-5-(4-methoxyphenyl)-1H-pyrimidin-6-ylidene]-3-methoxy-cyclohexa-2,4-dien-1-one::MLS000083254::SMR000047009::cid_5389961

SMILES COc1ccc(cc1)-c1cnc(N)nc1-c1ccc(OC)cc1O

InChI Key InChIKey=CKQBIKHXMSBFTE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 40958   

TargetFocal adhesion kinase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM40958((6E)-6-[2-amino-5-(4-methoxyphenyl)-1H-pyrimidin-6...)
Affinity DataIC50: 3.49E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2011
Entry Details
PCBioAssay
TargetProtein-tyrosine kinase 2-beta(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM40958((6E)-6-[2-amino-5-(4-methoxyphenyl)-1H-pyrimidin-6...)
Affinity DataIC50: 3.50E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetNuclear receptor coactivator 3(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM40958((6E)-6-[2-amino-5-(4-methoxyphenyl)-1H-pyrimidin-6...)
Affinity DataIC50: 7.07E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
TargetNuclear receptor coactivator 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM40958((6E)-6-[2-amino-5-(4-methoxyphenyl)-1H-pyrimidin-6...)
Affinity DataIC50: 1.69E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
TargetMitogen-activated protein kinase 10(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM40958((6E)-6-[2-amino-5-(4-methoxyphenyl)-1H-pyrimidin-6...)
Affinity DataIC50: 1.99E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay