BDBM409517 1-(Azetidin-1-yl)-2-[6-(3,4-difluorophenyl)-3-fluoro-pyrrolo[3,2-::US10377753, Example 382

SMILES Fc1cn(CC(=O)N2CCC2)c2cc(cnc12)-c1ccc(F)c(F)c1

InChI Key InChIKey=MNJFWXUQJIOQKG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 409517   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409517(1-(Azetidin-1-yl)-2-[6-(3,4-difluorophenyl)-3-fluo...)
Affinity DataIC50: 15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent