BDBM409475 4-[6-(4-Fluorophenyl)pyrrolo[3,2-b]pyridin-1-yl]butan-2-one;::US10377753, Example 340

SMILES CC(=O)CCn1ccc2ncc(cc12)-c1ccc(F)cc1

InChI Key InChIKey=LMFIZWUAYDLCQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 409475   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409475(4-[6-(4-Fluorophenyl)pyrrolo[3,2-b]pyridin-1-yl]bu...)
Affinity DataIC50: 12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent

LigandPNGBDBM409475(4-[6-(4-Fluorophenyl)pyrrolo[3,2-b]pyridin-1-yl]bu...)
Affinity DataIC50: 13nMAssay Description:Modulation of recombinant human GluN1/GluN2B NMDA receptor expressed in mammalian cells assessed as inhibition of glutamate/glycine-induced intracell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed