BDBM409237 6-(4-Methyl-2-thienyl)-1-[[5-(trifluoromethyl)-2-::US10377753, Example 137

SMILES Cc1csc(c1)-c1cnc2ccn(Cc3ccc(o3)C(F)(F)F)c2c1

InChI Key InChIKey=ILCDOFUXUXWKBB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 409237   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409237(6-(4-Methyl-2-thienyl)-1-[[5-(trifluoromethyl)-2- ...)
Affinity DataIC50: 20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent

LigandPNGBDBM409237(6-(4-Methyl-2-thienyl)-1-[[5-(trifluoromethyl)-2- ...)
Affinity DataIC50: 20nMAssay Description:Modulation of recombinant human GluN1/GluN2B NMDA receptor expressed in mammalian cells assessed as inhibition of glutamate/glycine-induced intracell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed