BDBM409035 3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-1-(3-(methylsulfonyl)phenyl)indolin-2-one::US10377746, Expl. 5

SMILES Cc1ncc(cn1)-c1ccc2c(c1)N(C(=O)C2(C)C)c1cccc(c1)S(C)(=O)=O

InChI Key InChIKey=UFJAQZCQSQPJMA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 409035   

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM409035(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-1-(3-(meth...)
Affinity DataIC50: 106nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent