BDBM408919 Methyl 1-(3,3-dimethyl-N-(4-(1-methyl-1H- pyrrolo[2,3-b]pyridin-5- yl)benzyl)butanamido)isoquinoline-6- carboxylate::US10377717, Compound 49

SMILES COC(=O)c1ccc2c(nccc2c1)N(Cc1ccc(cc1)-c1cnc2n(C)ccc2c1)C(=O)CC(C)(C)C

InChI Key InChIKey=DYGXBNBVLLACCV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408919   

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408919(Methyl 1-(3,3-dimethyl-N-(4-(1-methyl-1H- pyrrolo[...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent