BDBM408876 (E)-Methyl 3-(2-(trans-N-(4-(6- (dimethylamino) pyridin-3-yl)benzyl)-4- hydroxycyclohexanecarboxamido) pyridin-4-yl)acrylate::US10377717, Compound 7

SMILES COC(=O)\C=C\c1ccnc(c1)N(Cc1ccc(cc1)-c1ccc(nc1)N(C)C)C(=O)[C@H]1CC[C@H](O)CC1

InChI Key InChIKey=PHJARDFNFANMAM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408876   

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408876((E)-Methyl 3-(2-(trans-N-(4-(6- (dimethylamino) py...)
Affinity DataEC50:  5.50E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent