BDBM408875 (E)-Methyl 3-(2-(N-(4-(6- (dimethylamino)pyridin-3-yl) benzyl)tetrahydro- 2H-pyran-4-carboxamido) pyridin-4-yl)acrylate::US10377717, Compound 6

SMILES COC(=O)\C=C\c1ccnc(c1)N(Cc1ccc(cc1)-c1ccc(nc1)N(C)C)C(=O)C1CCOCC1

InChI Key InChIKey=DTHQKRDMFLGBHM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408875   

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408875((E)-Methyl 3-(2-(N-(4-(6- (dimethylamino)pyridin-3...)
Affinity DataEC50:  5.50E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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