BDBM408871 (E)-Methyl 3-(6-(N-((4'-(dimethylamino)-[1,1'- biphenyl]-4-yl)methyl)cyclo hexanecarboxamido) pyridin-2-yl)acrylate::US10377717, Compound 2

SMILES COC(=O)\C=C\c1cccc(n1)N(Cc1ccc(cc1)-c1ccc(cc1)N(C)C)C(=O)C1CCCCC1

InChI Key InChIKey=UIEYLXSOQXINMQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408871   

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408871((E)-Methyl 3-(6-(N-((4'-(dimethylamino)-[1,1'- bip...)
Affinity DataEC50: >1.00E+4nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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