BDBM408660 4-(4,4- dimethylpiperidin-1- yl)-2-oxo-1,2- dihydroquinoline-3- carbonitrile::US10376504, Example 1-11

SMILES CC1(C)CCN(CC1)c1c(C#N)c(=O)[nH]c2ccccc12

InChI Key InChIKey=NFLSUXGWBGDGBF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408660   

TargetPhosphodiesterase(Rhesus macaque)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM408660(US10376504, Example 1-11 | 4-(4,4- dimethylpiperid...)
Affinity DataKi:  26.3nMAssay Description:Rhesus PDE9A2 was amplified from rhesus whole brain cDNA (Biochain Institute) essentially as described in Hutson, et al. Neuropharmacology (2011) 61(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details
Go to US Patent