BDBM408585 US10358446, Compound 1::US10358446, Compound 3

SMILES C=CC(=O)N1CC[C@H](C1)n1c2ccncc2n(-c2ccc(Oc3ccccc3)cc2)c1=O

InChI Key InChIKey=YHCSNQVEOHUGIM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 408585   

TargetTyrosine-protein kinase BTK(Human)
Zibo Biopolar Changsheng Pharmaceutical

US Patent
LigandPNGBDBM408585(US10358446, Compound 3 | US10358446, Compound 1)
Affinity DataIC50: 55nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Blk(Human)
Zibo Biopolar Changsheng Pharmaceutical

US Patent
LigandPNGBDBM408585(US10358446, Compound 3 | US10358446, Compound 1)
Affinity DataIC50: 55nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Lyn(Human)
Zibo Biopolar Changsheng Pharmaceutical

US Patent
LigandPNGBDBM408585(US10358446, Compound 3 | US10358446, Compound 1)
Affinity DataIC50: 1.00E+4nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Lck(Human)
Zibo Biopolar Changsheng Pharmaceutical

US Patent
LigandPNGBDBM408585(US10358446, Compound 3 | US10358446, Compound 1)
Affinity DataIC50: 1.00E+4nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Zibo Biopolar Changsheng Pharmaceutical

US Patent
LigandPNGBDBM408585(US10358446, Compound 3 | US10358446, Compound 1)
Affinity DataIC50: 55nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Blk(Human)
Zibo Biopolar Changsheng Pharmaceutical

US Patent
LigandPNGBDBM408585(US10358446, Compound 3 | US10358446, Compound 1)
Affinity DataIC50: 550nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Lyn(Human)
Zibo Biopolar Changsheng Pharmaceutical

US Patent
LigandPNGBDBM408585(US10358446, Compound 3 | US10358446, Compound 1)
Affinity DataIC50: 1.00E+4nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent