BDBM408514 2-methyl-6-(1-(2-(2-methyl-4- (trifluoromethyl)phenyl)propan- 2-yl)-1H-1,2,3-triazol-4-yl) pyrimidin-4(3H)-one::US10358435, Example 31

SMILES Cc1nc(cc(=O)[nH]1)-c1cn(nn1)C(C)(C)c1ccc(cc1C)C(F)(F)F

InChI Key InChIKey=JPXZNTYRUWAXSW-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408514   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM408514(2-methyl-6-(1-(2-(2-methyl-4- (trifluoromethyl)phe...)
Affinity DataKi:  5.40nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
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Date in BDB:
6/21/2020
Entry Details
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