BDBM408087 US10336774, Example 78

SMILES COc1nccc(Sc2ncc(nc2N)N2CCC3(CCC[C@H]3N)CC2)c1Cl

InChI Key InChIKey=BVMGFHBKWCPQQH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408087   

LigandPNGBDBM408087(US10336774, Example 78)
Affinity DataIC50: 15nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
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