BDBM408085 US10336774, Example 76

SMILES N[C@@H]1CCCC11CCN(CC1)c1cnc(Sc2ccnnc2Cl)c(N)n1

InChI Key InChIKey=JMEPXTXUHBQMHC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408085   

LigandPNGBDBM408085(US10336774, Example 76)
Affinity DataIC50: 78nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
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