BDBM408083 US10336774, Example 73

SMILES NC1=NC2(CO1)CCN(CC2)c1cnc(Sc2ccnc(Cl)c2Cl)c(N)n1

InChI Key InChIKey=HABAXBHPCSEYQG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408083   

LigandPNGBDBM408083(US10336774, Example 73)
Affinity DataIC50: 20nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
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