BDBM40738 4-aminobutyl-(6-methoxy-8-quinolyl)amine::N'-(6-methoxy-8-quinolinyl)butane-1,4-diamine::N'-(6-methoxyquinolin-8-yl)butane-1,4-diamine::cid_231916

SMILES COc1cc(NCCCCN)c2ncccc2c1

InChI Key InChIKey=JVMFTXBPCRUPLQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 40738   

TargetHeat shock protein HSP 90-alpha(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM40738(N'-(6-methoxyquinolin-8-yl)butane-1,4-diamine | ci...)
Affinity DataIC50: 5.00E+4nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2011
Entry Details
PCBioAssay
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM40738(N'-(6-methoxyquinolin-8-yl)butane-1,4-diamine | ci...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Hsp90 in human MCF7 cells assessed as Her2 level after 24 hrs by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM40738(N'-(6-methoxyquinolin-8-yl)butane-1,4-diamine | ci...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Hsp90 in human MCF7 cell lysates assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed