BDBM406555 6-butyl-5-(3- cyclopropylphenyl)- 4-hydroxy-3-{5- [(2-methyl-1,3- thiazol-4- yl)methyl]-1,3,4- oxadiazol-2-yl}- 1,2-dihydropyridin- 2-one::US10336739, Example 150

SMILES CCCCc1[nH]c(=O)c(-c2nnc(Cc3csc(C)n3)o2)c(O)c1-c1cccc(c1)C(=O)NC(C)C

InChI Key InChIKey=QGUGMEBMQJIEEG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 406555   

TargetApelin receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM406555(6-butyl-5-(3- cyclopropylphenyl)- 4-hydroxy-3-{5- ...)
Affinity DataEC50:  5.5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent