BDBM406459 6-butyl-5-(2,6- dimethoxyphenyl)- 3-(5-{2-[3- (pyrazin-2-yl)- 1,2,4-oxadiazol-5- yl]ethyl}-1,3,4- oxadiazol-2- yl)pyridine-2,4-diol::US10336739, Example 52

SMILES CCCCc1nc(O)c(-c2nnc(CCc3nc(no3)-c3cnccn3)o2)c(O)c1-c1c(OC)cccc1OC

InChI Key InChIKey=WZPSCJJLVZVLQG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 406459   

TargetApelin receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM406459(6-butyl-5-(2,6- dimethoxyphenyl)- 3-(5-{2-[3- (pyr...)
Affinity DataEC50:  5.5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
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