BDBM406434 3-[5-(1,2- benzoxazol-3- ylmethyl)-1,3,4- oxadiazol-2-yl]-6- (but-3-en-1-yl)-5- (2,6- dimethoxyphenyl) pyridine-2,4-diol::US10336739, Example 27

SMILES COc1cccc(OC)c1-c1c(CCC=C)nc(O)c(-c2nnc(Cc3noc4ccccc34)o2)c1O

InChI Key InChIKey=UGCSYYLYYFIBQN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 406434   

TargetApelin receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM406434(3-[5-(1,2- benzoxazol-3- ylmethyl)-1,3,4- oxadiazo...)
Affinity DataEC50:  5.5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
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