BDBM406423 6-butyl-5-(2,6- dimethoxyphenyl)- 3-[5-(2- phenylpropan-2- yl)-1,3,4-oxadiazol- 2-yl]pyridine-2,4- diol::US10336739, Example 15

SMILES CCCCc1nc(O)c(-c2nnc(o2)C(C)(C)c2ccccc2)c(O)c1-c1c(OC)cccc1OC

InChI Key InChIKey=UIWDENZVZUNTRQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 406423   

TargetApelin receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM406423(6-butyl-5-(2,6- dimethoxyphenyl)- 3-[5-(2- phenylp...)
Affinity DataEC50:  5.5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent