BDBM406387 N-(tert-Butylsulfonyl)-2-((rac-trans)-4-hydroxy-3-((5-methyl-1,3,4-thiadiazol-2-yl)methyl)chroman-7-yl)benzamide::US10336733, Example 31

SMILES Cc1nnc(C[C@H]2COc3cc(ccc3[C@@H]2O)-c2ccccc2C(=O)NS(=O)(=O)C(C)(C)C)s1

InChI Key InChIKey=HEHRHYRMQAYMGB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 406387   

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandPNGBDBM406387(N-(tert-Butylsulfonyl)-2-((rac-trans)-4-hydroxy-3-...)
Affinity DataEC50:  556nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
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